1. A 48-year-old man with treatment-resistant schizophrenia has been relatively stable for the past.

1. A 48-year-old man with treatment-resistant schizophrenia has been relatively stable for the past 6 months on clozapine. On a routine follow-up visit, the patient is observed to be depressed and reports lack of appetite and insomnia, among other features of depression. The attending psychiatrist decides to treat the patient with antidepressants. Which of the following antidepressants would mandate particular caution in this patient? A. Mirtazapine B. Fluoxetine C. Sertraline D. Citalopram E. Trazodone