1. A 56-year-old man presents to the Emergency Department. He has been experiencing nose bleeds for.

1. A 56-year-old man presents to the Emergency Department. He has been experiencing nose bleeds for the past few days and episodes of haematuria. On examination you note evidence of a saddlenose deformity. He has no past medical history and is on no current medication. Cardiovascular, respiratory and abdominal examinations prove unremarkable. What is the most likely diagnosis? a) Wegener’s granulomatosis b) Acute tubular necrosis c) Tuberous sclerosis d) Goodpasture’s syndrome e) Systemic lupus erythematosus