A client who is receiving isoniazid (INH) reports tingling and numbness of the fingers and toes. The

A client who is receiving isoniazid (INH) reports tingling
and numbness of the fingers and toes. The nurse knows that these symptoms are
most likely due to the drug’s ability to:

1. Increase the sensitivity of nerve endings.

 2. Decrease the activity of pyridoxine (vitamin B 6 ).

 3. Accelerate the excretion of neurotransmitters.

 4. Enhance skin receptors for ascorbic acid (vitamin C).